Président : Pr Pierre-Jean GUILLAUSSEAU
Cliniciens:
Pierre-Jean GUILLAUSSEAU, Pascale MASSIN, Marie LALOI-MICHELIN
Julie BITU, Julien SAMUEL-LAJEUNESSE, Monique UZAN
Marie VIRALLY, Jean-Philippe KEVORKIAN, Hugues CHABRIAT (Paris, Lariboisière)
Bernard VIALETTES, Hervé NARBONNE (Marseille), José TIMSIT
Danièle DUBOIS-LAFORGUE, Agnès SOLA-GAZAGNES, Etienne LARGER (Paris, Hôtel Dieu)
Bernard BAUDUCEAU, Olivier DUPUY (Hôpital Bégin, Saint-Mandé), Sylvie CASANOVA (CCN, Saint Denis)
Monique MARTINEZ (Gonesse), Marielle VINCENOT (Saint Germain), Henri GIN (Bordeaux)
Eric BERTIN (Reims), Jean-Frédéric BLICKLE, Sylvie BOULLU-SANCHIS (Strasbourg)
Françoise LORENZINI, Béatrice DULY-BOUHANICK(Toulouse), Juliette CAHEN-VARSAUX
Pierre CHEDIN (Argenteuil), Guillaume CHARPENTIER, Jean-Pierre RIVELINE (Corbeil)
Christèle DERRIEN (Rennes), Pierre-Henri DUCLUZEAU (Lyon), André GRIMALDI (Paris, La Pitié)
Bruno GUERCI (Nancy), Edgar KALOUSTIAN (Compiègne), Arnaud MURAT (Nantes)
Frédérique OLIVIER (Cahors)
Généticiens :
Christine BELLANNE-CHANTELOT (Paris, La Pitié)
Véronique PAQUIS-FLUCKLINGER (Nice)
Agnès RÖTIG (Paris, Necker)
Étude clinique et génétique des diabètes mitochondriaux, évolution et complications. Registre national. Aide à la prise en charge diagnostique et thérapeutique des patients, et au dépistage. Mise en place de recommandations. Protocoles thérapeutiques.
PUBLICATIONS
- P. Massin, PJ. Guillausseau, B. Vialettes, V. Paquis, F. OrsinI, A.Grimaldi, A. Gaudric. Macular pattern dystrophy associated with a mutation of mitochondrial DNA. Am J. Ophthalmol 1995; 120: 247-248
- B. Vialettes, V. Paquis-Fluckinger, P. Silvestre-Aillaud, D.B. Dahan, J.F. Pelissier, F. Etchary-Bouyx, D. Raccah, H. Gin, PJ. Guillausseau, D. Vanuxen, F. Rossini, J. Pouget, P.Cozone, C. Desnuelle. Extra-pancreatic manifestations in diabetes secondary to mitochondrial DNA point mutation within the tRNA leu(UUR) gene.Diabetes Care 1995; 18: 1023-1028
- Massin, M.L. Virally, B. Vialettes, M. Paques, H. Gin, B. Porokhov, S. Caillat-Zucman, P. Froguel, V. Paquis-Fluckinger, A. Gaudric, PJ. Guillausseau. Prevalence of macular pattern dystrophy in maternally inherited diabetes and deafness. Ophthalmology 1999; 106: 1821-1827
- Guillausseau PJ, P.Massin, D.Dubois-Laforgue, J.Timsit, M.Virally, H.Gin, E.Bertin, J.F.Blickle, B.Bouhanick, J.Cahen-Varsaux, S.Caillat-Zucman, G.Charpentier, P.Chedin, C.Derrien, P.Ducluzeau, A.Grimaldi, B.Guerci, E.Kaloustian, A.Murat, F.Olivier, M.Paques, V.Paquis-Flucklinger, B.Porokhov, J.Samuel-Lajeunesse, B.Vialettes. Maternally Inherited Diabetes and Deafness: A multicenter Study. Ann Intern Med 2001;134: 721-72
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Guillausseau PJ, Dubois-Laforgue D, Massin P, Laloi-Michelin M, Bellanne-Chantelot C, Gin H, Bertin E, Blickle JF, Bauduceau B, Bouhanick B, Cahen-Varsaux J, Casanova S, Charpentier G, Chedin P, Derrien C, Grimaldi A, Guerci B, Kaloustian E, Lorenzini F, Murat A, Olivier F, Paques M, Paquis-Flucklinger V, Tielmans A, Vincenot M, Vialettes B, Timsit J; GEDIAM, Mitochondrial Diabetes French Study Group. Heterogeneity of diabetes phenotype in patients with 3243 bp mutation of mitochondrial DNA (Maternally Inherited Diabetes and Deafness or MIDD). Diabetes Metab. 2004; 30:181-6
- Guillausseau PJ, Massin P, Bellanné-Chantelot C, Timsit J. Diabètes par anomalies du génome mitochondrial. In Grimaldi A. Traité de Diabétologie. Flammarion Ed. (Paris) 2005 pp 884-891
- Mikol J, Guillausseau PJ, Massin P. Diabetes and mitochondrial cytopathies: pathological studies. Ann Pathol 2005, 25:292-298
- Guillausseau PJ, Laloi-Michelin M, Virally M, Massin P, Bellanné-Chantelot C, Timsit J. Diabètes mitochondriaux. Encycl Med Chir ORL, Elsevier SAS, Paris, 2005, Endocrinologie-Nutrition, 10-366-D-25, 2005
- Laloi-Michelin M, Virally M, Jardel C, Meas T, Ingster-Moati I, Lombès A, Massin P, Chabriat H, Tielmans A, Mikol J, Guillausseau PJ. Kearns Sayre Syndrome: an unusual form of mitochondrial diabetes. Diabetes Metab 2006; 32: 182-86
- P Massin, D Dubois-Laforgue, T. Meas, M Laloi-Michelin, H Gin, B Bauduceau, C Bellanne-Chantelot, E Bertin, J-F Blickle, B Bouhanick, J Cahen-Varsaux, S Casanova, G. Charpentier, P. Chedin, O. Dupuy, A Grimaldi, B Guerci, E Kaloustian, A Lecleire-Collet, F Lorenzini, A Murat, H Narbonne, F Olivier, V Paquis-Flucklinger, M Virally, M Vincenot, B Vialettes, J Timsit, PJ Guillausseau. Retinal and renal complications in patients with 3243bp mutation of mitochondrial DNA (Maternally Inherited Diabetes and Deafness). A case control study. Diabetologia 2008; 51: 1664-70.
- C Ambonville, T Meas, A Lecleire-Collet, M Laloi-Michelin, M Virally, JP Kevorkian, M Paques, P Massin, PJ Guillausseau. Macular pattern dystrophy in MIDD. Long-term follow-up. Diabetes Metab 2008; 34: 389-91.
- M. Laloi-Michelin, T. Meas , C. Ambonville, C. Bellanné-Chantelot, S. Beaufils, P Massin, B. Vialettes, H. Gin, J. Timsit, B. Bauduceau, L. Bernard, E. Bertin, JF. Blickle, J. Cahen-Varsaux, A. Cailleba, S. Casanova, P. Cathebras, G. Charpentier, P. Chedin, T. Crea, B Delemer, D. Dubois-laforgue, F. Duchemin, Ph. Ducluzeau, B. Bouhanick, L. Dusselier, T. Gabreau, A. Grimaldi, B. Guerci, V. Jacquin, E. Kaloustian, E. Larger, A Lecleire-Collet, F. Lorenzini, J. Louis, J. Mausset, A. Murat, S. Nadler-Fluteau, F. Olivier, V. Paquis-Flucklinger, D. Paris-Bockel, I. Raynaud, Y. Reznik, JP Riveline, S. Schneebeli, E. Sonnet, A Sola-Gazagnes, JL. Thomas, B. Trabulsi, M. Virally, PJ Guillausseau. The clinical variability of maternally inherited diabetes and deafness (MIDD) is associated with the degree of heteroplasmy in blood leukocytes. J Clin Endocrinol Metab 2009; 94: 3025-30.
- Guillausseau PJ, Laloi-Michelin M, Meas T, M.Virally, J Bitu, P.Massin, C.Bellanne-Chantelot, J.Timsit. Diabètes mitochondriaux. EMC (Elsevier SAS, Paris) Endocrinologie-Nutrition, 2011-10-18 (in press)
COMMUNICATIONS DANS DES CONGRES NATIONAUX ET INTERNATIONAUX
- Virally M, Massin P, Vialettes B, Bertin E, Cahen J, Charpentier G, Chedin P, Derrien C, Dollfus H, Ducluzeau P, Gin H, Grimaldi A, Guerci B, Kaloustian A, Melki F, Paques M, Porokhov B, Pousset MC, Timsit J, Guillausseau PJ. Prevalence of retinal, but not of renal microvascular complications is lower in Maternally Inherited Diabetes and Deafness. 7th Meeting of the MGSD, Marrakech, 30 mars-1er avril 2000.
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